ABCMdb

PMID: 15003516

Pelletier M, Cartron PF, Delaval F, Meflah K, Vallette FM, Oliver L
Caspase 3 activation is controlled by a sequence located in the N-terminus of its large subunit.
Biochem Biophys Res Commun. 2004 Mar 26;316(1):93-9., [PubMed]

Sentences

No. Mutations Sentence Comment

61 ABCC8 p.Leu31Met Oligonucleotides C3/I31M, C3/L31M, C3/ L33W, C3/N35T, and C3/S36G were used with C3 AS to generate the corresponding single acid amino substitution in the wild-type C3 sequence. Login to comment 62 ABCC8 p.Leu31Met Oligonucleotides C3/I31M, C3/L31M, C3/ L33W, C3/N35T, and C3/S36G were used with C3 AS to generate the corresponding single acid amino substitution in the wild-type C3 sequence. Login to comment 136 ABCC1 p.Asn35Thr On the other hand, the DEVDase activity was significantly decreased by the substitution of a Leu for a Trp at position 33 (L33W, P &#bc; 0:0133), by a Ser for a Gly at position 36 (S36G, P &#bc; 0:0133) or by that of an Asn for a Thr at position 35 (N35T, P &#bc; 0:003). Login to comment 137 ABCC1 p.Asn35Thr On the other hand, the DEVDase activity was significantly decreased by the substitution of a Leu for a Trp at position 33 (L33W, P ¼ 0:0133), by a Ser for a Gly at position 36 (S36G, P ¼ 0:0133) or by that of an Asn for a Thr at position 35 (N35T, P ¼ 0:003). Login to comment