PMID: 11940086

Zwarts KY, Clee SM, Zwinderman AH, Engert JC, Singaraja R, Loubser O, James E, Roomp K, Hudson TJ, Jukema JW, Kastelein JJ, Hayden MR
ABCA1 regulatory variants influence coronary artery disease independent of effects on plasma lipid levels.
Clin Genet. 2002 Feb;61(2):115-25., [PubMed]
Sentences
No. Mutations Sentence Comment
22 ABCA1 p.Arg219Lys
X
ABCA1 p.Arg219Lys 11940086:22:19
status: NEW
view ABCA1 p.Arg219Lys details
 Interestingly, the R219K cSNP is associated with decreased TG, increased HDL-C and a decreased severity of CAD, which is compatible with a net increase in transporter function (16). Login to comment