PMID: 11927666

Linsdell P, Gong X
Multiple inhibitory effects of Au(CN)(2-) ions on cystic fibrosis transmembrane conductance regulator Cl(-) channel currents.
J Physiol. 2002 Apr 1;540(Pt 1):29-38., 2002-04-01 [PubMed]
Sentences
No. Mutations Sentence Comment
141 ABCC7 p.Lys1250Ala
X
ABCC7 p.Lys1250Ala 11927666:141:41
status: NEW
view ABCC7 p.Lys1250Ala details
 A similar strategy using the CFTR mutant K1250A, which shows prolonged openings similar to that of wild type CFTR after locking the channels open with PPi (Gunderson & Kopito, 1995), has been used to dissociate open channel blocking from gating events at the single channel level (Zhou et al. 2001). Login to comment