PMID: 11244086

Ostedgaard LS, Baldursson O, Welsh MJ
Regulation of the cystic fibrosis transmembrane conductance regulator Cl- channel by its R domain.
J Biol Chem. 2001 Mar 16;276(11):7689-92. Epub 2001 Jan 23., 2001-03-16 [PubMed]
Sentences
No. Mutations Sentence Comment
35 ABCC7 p.Ser737Ala
X
ABCC7 p.Ser737Ala 11244086:35:35
status: NEW
view ABCC7 p.Ser737Ala details
ABCC7 p.Ser737Ala
X
ABCC7 p.Ser737Ala 11244086:35:107
status: NEW
view ABCC7 p.Ser737Ala details
 In excised, cell-free patches, the S737A mutant reduced Po (20), but in Xenopus oocytes and epithelia, the S737A mutant increased cAMP-stimulated current (21, 23). Login to comment