PMID: 10758006

Julien M, Gros P
Nucleotide-induced conformational changes in P-glycoprotein and in nucleotide binding site mutants monitored by trypsin sensitivity.
Biochemistry. 2000 Apr 18;39(15):4559-68., 2000-04-18 [PubMed]
Sentences
No. Mutations Sentence Comment
232 ABCB1 p.Asp555Asn
X
ABCB1 p.Asp555Asn 10758006:232:64
status: NEW
view ABCB1 p.Asp555Asn details
ABCB1 p.Asp1200Asn
X
ABCB1 p.Asp1200Asn 10758006:232:74
status: NEW
view ABCB1 p.Asp1200Asn details
ABCB1 p.Asp1200Asn
X
ABCB1 p.Asp1200Asn 10758006:232:152
status: NEW
view ABCB1 p.Asp1200Asn details
 Additional photolabeling experiments using the Walker B mutants D555N and D1200N showed that in contrast to results from Urbatsch et al. (15), only the D1200N mutant can be photolabeled under binding conditions with all the label being present at the NBD1 (16). Login to comment