ABCMdb

PMID: 10518014

Zerhusen B, Ma J
Function of the second nucleotide-binding fold in the CFTR chloride channel.
FEBS Lett. 1999 Oct 8;459(2):177-85., [PubMed]

Sentences

No. Mutations Sentence Comment

211 ABCC7 p.Pro574His Mutations in di&#a1;erent regions of CFTR, either changes in single amino acids, i.e. vF508 and P574H [17], or regional deletions, i.e. vexon5 and v19 [20,28], all lead to di&#a4;culty in proper folding and have a signi'cant impact on the processing of CFTR proteins. Login to comment 212 ABCC7 p.Pro574His Mutations in di¡erent regions of CFTR, either changes in single amino acids, i.e. vF508 and P574H [17], or regional deletions, i.e. vexon5 and v19 [20,28], all lead to di¤culty in proper folding and have a signi'cant impact on the processing of CFTR proteins. Login to comment