PMID: 10197533

Zerangue N, Schwappach B, Jan YN, Jan LY
A new ER trafficking signal regulates the subunit stoichiometry of plasma membrane K(ATP) channels.
Neuron. 1999 Mar;22(3):537-48., [PubMed]
Sentences
No. Mutations Sentence Comment
241 ABCC8 p.Leu368Ala
X
ABCC8 p.Leu368Ala 10197533:241:118
status: NEW
view ABCC8 p.Leu368Ala details
 Kir6.2⌬12, Kir6.2⌬14, Kir6.2⌬16, Kir6.2⌬18, R365A, GP366/367AA, LR368/369AA, KR370/371AA, L368A, R369A, R369K, K370A, K370R,An important but poorly understood aspect of ion K370H, K370N, K370Q, K370W, K370I, K370E, R371A, R371K, promoter], 1% dextrose, and 1.5% Sea-KEM agarose, pH adjusted to 6 with phosphoric acid) (Uozumi et al., 1995).RR369/371KK, and S372A were then constructed by ligating in complementary oligonucleotides with appropriate overhangs (Figure 3B [b-d and f]). Login to comment