Mutations in ABCB6
reference sequence
Region |
Mutation |
|
|
Publications |
Sentences |
MutMiner_hits |
SNAP2 |
PROVEAN |
Effect_ExpVar |
ELa |
p.Gly
12
Val
|
details |
homologous mutations |
1 |
1 |
1 |
N |
N |
? |
ELa |
p.Cys
26
Ala
|
details |
homologous mutations |
1 |
10 |
10 |
D |
D |
? |
ELa |
p.Cys
26
His
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
ELa |
p.Cys
26
Ser
|
details |
homologous mutations |
1 |
2 |
4 |
D |
D |
? |
TMD0,THa |
p.Gly
40
Ala
|
details |
homologous mutations |
1 |
1 |
1 |
N |
N |
? |
TMD0,CLa |
p.Cys
50
Ala
|
details |
homologous mutations |
1 |
6 |
10 |
N |
N |
? |
TMD0,CLa |
p.Ala
57
Thr
|
details |
homologous mutations |
4 |
11 |
11 |
N |
N |
D |
TMD0,THb |
p.Pro
72
Arg
|
details |
homologous mutations |
1 |
1 |
1 |
D |
N |
? |
TMD0,THc |
p.Cys
120
Ala
|
details |
homologous mutations |
1 |
1 |
2 |
N |
N |
? |
TMD0,ELc |
p.Ser
170
Gly
|
details |
homologous mutations |
3 |
8 |
8 |
N |
N |
D |
TMD0,THe |
p.Arg
192
Trp
|
details |
homologous mutations |
1 |
45 |
54 |
D |
D |
? |
TMD0,THe |
p.Arg
192
Gln
|
details |
homologous mutations |
1 |
4 |
4 |
D |
D |
|
TMD1,TH1 |
p.Arg
276
Trp
|
details |
homologous mutations |
1 |
14 |
14 |
D |
D |
? |
TMD1,TH2 |
p.Ser
322
Lys
|
details |
homologous mutations |
2 |
5 |
5 |
N |
D |
? |
TMD1,TH2 |
p.Ser
322
Leu
|
details |
homologous mutations |
1 |
1 |
1 |
N |
D |
? |
TMD1,TH2 |
p.Ser
322
Arg
|
details |
homologous mutations |
1 |
3 |
3 |
N |
D |
? |
TMD1,CL1 |
p.Leu
356
Pro
|
details |
homologous mutations |
3 |
8 |
8 |
D |
D |
D |
TMD1,CL1 |
p.Arg
375
Trp
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,CL1 |
p.Arg
375
Gln
|
details |
homologous mutations |
2 |
2 |
2 |
D |
D |
? |
TMD1,TH4 |
p.Tyr
424
His
|
details |
homologous mutations |
1 |
3 |
3 |
D |
D |
? |
TMD1,CL2 |
p.Ala
453
Val
|
details |
homologous mutations |
2 |
7 |
7 |
D |
D |
? |
CL3 |
p.Gln
555
Lys
|
details |
homologous mutations |
2 |
4 |
4 |
D |
D |
D |
CL3 |
p.Gly
579
Glu
|
details |
homologous mutations |
3 |
8 |
8 |
N |
D |
D |
CL3 |
p.Gly
588
Ser
|
details |
homologous mutations |
1 |
16 |
17 |
D |
D |
? |
CL3,NBD1,WA1 |
p.Gly
628
Ala
|
details |
homologous mutations |
1 |
12 |
12 |
D |
D |
? |
CL3,NBD1,WA1 |
p.Lys
629
Gly
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3,NBD1,WA1 |
p.Lys
629
Met
|
details |
homologous mutations |
2 |
3 |
3 |
D |
D |
? |
CL3,NBD1,WA1 |
p.Lys
629
Arg
|
details |
homologous mutations |
1 |
12 |
12 |
D |
D |
? |
CL3,NBD1,WA1 |
p.Lys
629
Ala
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3,NBD1 |
p.Leu
811
Val
|
details |
homologous mutations |
4 |
12 |
13 |
D |
D |
D |