ABCB1 p.Ala57Leu

Predicted by SNAP2: C: N (97%), D: N (53%), E: N (57%), F: N (93%), G: N (93%), H: N (72%), I: N (82%), K: N (57%), L: N (87%), M: N (93%), N: N (66%), P: D (53%), Q: N (66%), R: N (61%), S: N (93%), T: N (87%), V: N (82%), W: N (53%), Y: N (72%),
Predicted by PROVEAN: C: N, D: D, E: N, F: N, G: N, H: D, I: N, K: N, L: N, M: N, N: N, P: N, Q: N, R: N, S: N, T: N, V: N, W: N, Y: N,

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[hide] Loo TW, Bartlett MC, Clarke DM
Arginines in the first transmembrane segment promote maturation of a P-glycoprotein processing mutant by hydrogen bond interactions with tyrosines in transmembrane segment 11.
J Biol Chem. 2008 Sep 5;283(36):24860-70. Epub 2008 Jul 2., 2008-09-05 [PMID:18596043]

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