ABCB1 p.Ala57Leu
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PMID: 18596043
[PubMed]
Loo TW et al: "Arginines in the first transmembrane segment promote maturation of a P-glycoprotein processing mutant by hydrogen bond interactions with tyrosines in transmembrane segment 11."
No.
Sentence
Comment
270
results are consistent with a previous study that examined the effects of arginine substitutions to residues Ala-57 to Leu-65 in TM1 on drug transport by P-gp (43).
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ABCB1 p.Ala57Leu 18596043:270:109
status: NEW