ABCB1 p.Leu322Ile

Predicted by SNAP2: A: N (66%), C: D (53%), D: D (75%), E: D (75%), F: N (78%), G: D (66%), H: D (53%), I: N (93%), K: D (75%), M: N (93%), N: D (66%), P: D (75%), Q: N (66%), R: N (72%), S: D (59%), T: D (59%), V: N (87%), W: D (71%), Y: D (63%),
Predicted by PROVEAN: A: D, C: D, D: D, E: D, F: D, G: D, H: D, I: N, K: D, M: N, N: D, P: D, Q: D, R: D, S: D, T: D, V: N, W: D, Y: D,

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[hide] Ambudkar SV, Dey S, Hrycyna CA, Ramachandra M, Pastan I, Gottesman MM
Biochemical, cellular, and pharmacological aspects of the multidrug transporter.
Annu Rev Pharmacol Toxicol. 1999;39:361-98., [PMID:10331089]

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[hide] Shoshani T, Zhang S, Dey S, Pastan I, Gottesman MM
Analysis of random recombination between human MDR1 and mouse mdr1a cDNA in a pHaMDR-dihydrofolate reductase bicistronic expression system.
Mol Pharmacol. 1998 Oct;54(4):623-30., [PMID:9765504]

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[hide] Hrycyna CA
Molecular genetic analysis and biochemical characterization of mammalian P-glycoproteins involved in multidrug resistance.
Semin Cell Dev Biol. 2001 Jun;12(3):247-56., [PMID:11428917]

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[hide] Zhou Y, Gottesman MM, Pastan I
The extracellular loop between TM5 and TM6 of P-glycoprotein is required for reactivity with monoclonal antibody UIC2.
Arch Biochem Biophys. 1999 Jul 1;367(1):74-80., [PMID:10375401]

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