ABCC1 p.His1486Tyr

Predicted by SNAP2: A: D (85%), C: D (85%), D: D (91%), E: D (91%), F: D (91%), G: D (85%), I: D (91%), K: D (85%), L: D (91%), M: D (85%), N: D (80%), P: D (91%), Q: D (80%), R: D (85%), S: D (80%), T: D (85%), V: D (85%), W: D (91%), Y: D (85%),
Predicted by PROVEAN: A: D, C: D, D: D, E: D, F: D, G: D, I: D, K: D, L: D, M: D, N: D, P: D, Q: D, R: D, S: D, T: D, V: D, W: D, Y: D,

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[hide] Yang R, Chang XB
Hydrogen-bond formation of the residue in H-loop of the nucleotide binding domain 2 with the ATP in this site and/or other residues of multidrug resistance protein MRP1 plays a crucial role during ATP-dependent solute transport.
Biochim Biophys Acta. 2007 Feb;1768(2):324-35. Epub 2006 Nov 18., [PMID:17187755]

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