ABCC1 p.Lys347Leu

Predicted by SNAP2: A: N (72%), C: N (57%), D: N (78%), E: N (72%), F: D (59%), G: N (87%), H: N (82%), I: N (53%), L: N (53%), M: N (72%), N: N (87%), P: D (59%), Q: N (87%), R: N (97%), S: N (97%), T: N (82%), V: N (53%), W: D (63%), Y: D (53%),
Predicted by PROVEAN: A: N, C: D, D: D, E: N, F: D, G: D, H: D, I: D, L: D, M: D, N: N, P: D, Q: N, R: N, S: N, T: N, V: D, W: D, Y: D,

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[hide] Haimeur A, Conseil G, Deeley RG, Cole SP
Mutations of charged amino acids in or near the transmembrane helices of the second membrane spanning domain differentially affect the substrate specificity and transport activity of the multidrug resistance protein MRP1 (ABCC1).
Mol Pharmacol. 2004 Jun;65(6):1375-85., [PMID:15155831]

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