ABCC7 p.Leu1436Asp

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PMID: 24191035 [PubMed] Bozoky Z et al: "Regulatory R region of the CFTR chloride channel is a dynamic integrator of phospho-dependent intra- and intermolecular interactions."
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117 Q1411D; L1436D; and H1402A) designed by SGX Inc. We find similar patterns of R region binding to NBD2 as for NBD1 (Fig. 1E), identifying NBD2 as a direct binding partner for R region and implying that the NBDs have similar binding properties.
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ABCC7 p.Leu1436Asp 24191035:117:8
status: NEW
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239 The NBD2 domain of human CFTR (aa 1193-1445, Q1280E; Y1307N; Q1411D; H1402A; and L1436D), a construct with solubilizing mutations designed by SGX, Inc., was encoded on a pET-SUMO plasmid (Invitrogen).
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ABCC7 p.Leu1436Asp 24191035:239:81
status: NEW
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