ABCC7 p.Gln1280Glu
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PMID: 23378596
[PubMed]
Hunt JF et al: "Cystic fibrosis transmembrane conductance regulator (ABCC7) structure."
No.
Sentence
Comment
289
Improvements in the yield of soluble protein were obtained by introducing the hydrolytically inactivating H1402A mutation in ATPase active site of hNBD2 plus a series of "solubilizing" mutations on its surface (Q1280E/ Y1307N/W1310H/Q1411D) (X Zhao, S Atwell, JF Hunt, et al., unpubl.).
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ABCC7 p.Gln1280Glu 23378596:289:211
status: NEW
PMID: 24191035
[PubMed]
Bozoky Z et al: "Regulatory R region of the CFTR chloride channel is a dynamic integrator of phospho-dependent intra- and intermolecular interactions."
No.
Sentence
Comment
110
Binding was also probed to human CFTR NBD2 using a construct containing five solubilizing mutations (aa 1193-1445, Q1280E; Y1307N; Fig. 2.
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ABCC7 p.Gln1280Glu 24191035:110:115
status: NEW239 The NBD2 domain of human CFTR (aa 1193-1445, Q1280E; Y1307N; Q1411D; H1402A; and L1436D), a construct with solubilizing mutations designed by SGX, Inc., was encoded on a pET-SUMO plasmid (Invitrogen).
X
ABCC7 p.Gln1280Glu 24191035:239:45
status: NEW