ABCC7 p.Lys615Ala

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PMID: 11597353 [PubMed] Boucherot A et al: "Role of CFTR's PDZ1-binding domain, NBF1 and Cl(-) conductance in inhibition of epithelial Na(+) channels in Xenopus oocytes."
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38 Using similar PCR techniques, the NBF1 mutants of human CFTR vF508, G551D, S466L, K464A, D572N, KH483/484AA, R487Q, R516A, KR598/600GA, KK611/612AA and K615A were in vitro synthesized (Quickchange, Stratagene).
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ABCC7 p.Lys615Ala 11597353:38:152
status: NEW
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116 The CFTR mutants K646A, R487Q, G551D, D572N and K615A did not generate signi'cant CFTR Cl3 conductances.
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ABCC7 p.Lys615Ala 11597353:116:48
status: NEW
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172 Furthermore, NBF1 sequences which could potentially serve as activator sequences for G proteins were mutated (KR598/600GA, KK611/ 612AA, K615A).
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ABCC7 p.Lys615Ala 11597353:172:137
status: NEW
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