ABCG1 p.Ser388Ala

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PMID: 22872754 [PubMed] Gelissen IC et al: "Protein kinase A modulates the activity of a major human isoform of ABCG1."
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139 HDL-induced cholesterol export from cells expressing ABCG1(+12)-S388A and ABCG1(+12)- S390A was similar to that of cholesterol export from wild-type ABCG1(+12) cells (Fig. 4).
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ABCG1 p.Ser388Ala 22872754:139:64
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140 Furthermore, upon incubation with H89, cholesterol export from cells expressing the S388A or S390A mutants was increased to a level similar to that of the parental ABCG1(+12).
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ABCG1 p.Ser388Ala 22872754:140:84
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177 H89 significantly increased cholesterol export from cells expressing ABCG1(+12), S388A, and S390A (P < 0.05), but not ABCG1(afa;12) or S389A.
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ABCG1 p.Ser388Ala 22872754:177:81
status: NEW
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