ABCC2 p.Thr420Asn

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PMID: 24145529 [PubMed] Obonaga R et al: "Treatment failure and miltefosine susceptibility in dermal leishmaniasis caused by Leishmania subgenus Viannia species."
No. Sentence Comment
93 The presence of C1259A (T420N) and T2567C (L856P) polymorphisms in the LbMT gene, previously reported to be associated with experimentally derived miltefosine resistance (9), and G630A (W210*) analyzed in VL and post-kala-azar dermal leishmaniasis (PKDL) strains of L. donovani (19) were characterized by sequence analysis of PCR products.
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ABCC2 p.Thr420Asn 24145529:93:24
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95 PCR was carried out using primer sets W210*-F (5=-AGGCGTTCATTG ACACATGC-3=) and W210*-R (5=-TACAGGAACTGGTTCAGCGAC- 3=); T420N-F (5=-TGGAGTACATGAACAACCGCT-3=) and T420N-R (5=- CTCTTCCTCCTTGCGCAGTC-3=), and L856P-F (5=-TCATTGGGCTGG AAGGTTCA-3=) and L856P-R (5=-GTGTTAGTCCCGAGAAGCCA-3=).
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ABCC2 p.Thr420Asn 24145529:95:120
status: NEW
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ABCC2 p.Thr420Asn 24145529:95:162
status: NEW
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