ABCA1 p.Thr1389Cys
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PMID: 24867987
[PubMed]
Ricardo E et al: "In vivo and in vitro acquisition of resistance to voriconazole by Candida krusei."
No.
Sentence
Comment
194
On the other hand, the heterozygous alteration detected (T1389C), which is located outside the azole binding site, according to previously published data, was found in both susceptible and resistant strains (32).
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ABCA1 p.Thr1389Cys 24867987:194:57
status: NEW
PMID: 26308936
[PubMed]
He X et al: "Overexpression of Both ERG11 and ABC2 Genes Might Be Responsible for Itraconazole Resistance in Clinical Isolates of Candida krusei."
No.
Sentence
Comment
131
The 6 synonymous mutations can appear in both non-resistant and resistant strains, and all the C.krusei strains presented C642T, T1389C, and G1536C mutations.
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ABCA1 p.Thr1389Cys 26308936:131:129
status: NEW202 Our data showed that there were 7-point mutations existing in ERG11 gene of C. krusei, including 6 synonymous mutations (C51T, C642T, A756T, T939C, T1389C, and G1536C) and 1 missense mutation (C44T).
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ABCA1 p.Thr1389Cys 26308936:202:148
status: NEW205 Moreover, in our study, all the non-resistant and resistant C.krusei strains presented C642T, T1389C, G1536C mutations.
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ABCA1 p.Thr1389Cys 26308936:205:94
status: NEW206 Ricardo et al. [19] also reported that T1389C mutation occurred in all the experimental strains.
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ABCA1 p.Thr1389Cys 26308936:206:39
status: NEW134 The 6 synonymous mutations can appear in both non-resistant and resistant strains, and all the C.krusei strains presented C642T, T1389C, and G1536C mutations.
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ABCA1 p.Thr1389Cys 26308936:134:129
status: NEW208 Our data showed that there were 7-point mutations existing in ERG11 gene of C. krusei, including 6 synonymous mutations (C51T, C642T, A756T, T939C, T1389C, and G1536C) and 1 missense mutation (C44T).
X
ABCA1 p.Thr1389Cys 26308936:208:148
status: NEW211 Moreover, in our study, all the non-resistant and resistant C.krusei strains presented C642T, T1389C, G1536C mutations.
X
ABCA1 p.Thr1389Cys 26308936:211:94
status: NEW212 Ricardo et al. [19] also reported that T1389C mutation occurred in all the experimental strains.
X
ABCA1 p.Thr1389Cys 26308936:212:39
status: NEW