PMID: 26308936

He X, Zhao M, Chen J, Wu R, Zhang J, Cui R, Jiang Y, Chen J, Cao X, Xing Y, Zhang Y, Meng J, Deng Q, Sui T
Overexpression of Both ERG11 and ABC2 Genes Might Be Responsible for Itraconazole Resistance in Clinical Isolates of Candida krusei.
PLoS One. 2015 Aug 26;10(8):e0136185. doi: 10.1371/journal.pone.0136185. eCollection 2015., [PubMed]
Sentences
No. Mutations Sentence Comment
131 ABCA1 p.Thr1389Cys
X
ABCA1 p.Thr1389Cys 26308936:131:129
status: NEW
view ABCA1 p.Thr1389Cys details
The 6 synonymous mutations can appear in both non-resistant and resistant strains, and all the C.krusei strains presented C642T, T1389C, and G1536C mutations. Login to comment
134 ABCA1 p.Thr1389Cys
X
ABCA1 p.Thr1389Cys 26308936:134:129
status: NEW
view ABCA1 p.Thr1389Cys details
The 6 synonymous mutations can appear in both non-resistant and resistant strains, and all the C.krusei strains presented C642T, T1389C, and G1536C mutations. Login to comment
202 ABCA1 p.Thr1389Cys
X
ABCA1 p.Thr1389Cys 26308936:202:148
status: NEW
view ABCA1 p.Thr1389Cys details
Our data showed that there were 7-point mutations existing in ERG11 gene of C. krusei, including 6 synonymous mutations (C51T, C642T, A756T, T939C, T1389C, and G1536C) and 1 missense mutation (C44T). Login to comment
205 ABCA1 p.Thr1389Cys
X
ABCA1 p.Thr1389Cys 26308936:205:94
status: NEW
view ABCA1 p.Thr1389Cys details
Moreover, in our study, all the non-resistant and resistant C.krusei strains presented C642T, T1389C, G1536C mutations. Login to comment
206 ABCA1 p.Thr1389Cys
X
ABCA1 p.Thr1389Cys 26308936:206:39
status: NEW
view ABCA1 p.Thr1389Cys details
Ricardo et al. [19] also reported that T1389C mutation occurred in all the experimental strains. Login to comment
208 ABCA1 p.Thr1389Cys
X
ABCA1 p.Thr1389Cys 26308936:208:148
status: NEW
view ABCA1 p.Thr1389Cys details
Our data showed that there were 7-point mutations existing in ERG11 gene of C. krusei, including 6 synonymous mutations (C51T, C642T, A756T, T939C, T1389C, and G1536C) and 1 missense mutation (C44T). Login to comment
211 ABCA1 p.Thr1389Cys
X
ABCA1 p.Thr1389Cys 26308936:211:94
status: NEW
view ABCA1 p.Thr1389Cys details
Moreover, in our study, all the non-resistant and resistant C.krusei strains presented C642T, T1389C, G1536C mutations. Login to comment
212 ABCA1 p.Thr1389Cys
X
ABCA1 p.Thr1389Cys 26308936:212:39
status: NEW
view ABCA1 p.Thr1389Cys details
Ricardo et al. [19] also reported that T1389C mutation occurred in all the experimental strains. Login to comment