ABCG5 p.Lys92Met
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PMID: 17055487
[PubMed]
Muller M et al: "Co-expression of human ABCG5 and ABCG8 in insect cells generates an androstan stimulated membrane ATPase activity."
No.
Sentence
Comment
57
Co-expression of the wtABCG5 and wtABCG8 as well as K92M-ABCG5 and wtABCG8 was carried out by using different ratios of the corresponding recombinant baculovirus supernatants.
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ABCG5 p.Lys92Met 17055487:57:52
status: NEW95 As a negative control, we used the co-expression of a Walker A mutant (ABCG5-K92M) of ABCG5 with the wild-type ABCG8 (G5K92M/G8).
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ABCG5 p.Lys92Met 17055487:95:77
status: NEW118 The specific, androgen-stimulated ATPase activity of the ABCG5/ABCG8 heterodimer was abolished when a key lysine was changed to methionine (K92M) in the Walker A motif of ABCG5.
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ABCG5 p.Lys92Met 17055487:118:140
status: NEW58 Co-expression of the wtABCG5 and wtABCG8 as well as K92M-ABCG5 and wtABCG8 was carried out by using different ratios of the corresponding recombinant baculovirus supernatants.
X
ABCG5 p.Lys92Met 17055487:58:52
status: NEW96 As a negative control, we used the co-expression of a Walker A mutant (ABCG5-K92M) of ABCG5 with the wild-type ABCG8 (G5K92M/G8).
X
ABCG5 p.Lys92Met 17055487:96:77
status: NEW119 The specific, androgen-stimulated ATPase activity of the ABCG5/ABCG8 heterodimer was abolished when a key lysine was changed to methionine (K92M) in the Walker A motif of ABCG5.
X
ABCG5 p.Lys92Met 17055487:119:140
status: NEW