ABCB4 p.Gly432Cys

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PMID: 10806188 [PubMed] Loo TW et al: "Drug-stimulated ATPase activity of human P-glycoprotein is blocked by disulfide cross-linking between the nucleotide-binding sites."
No. Sentence Comment
84 Residue in NBD1 Cys-1074 Residue in NBD2 Cys-431 L425C -a V426C - V1069C - G427C ϩb G1070C - N428C - S1071C - S429C - S1072C - G430C - G1073C - Cys-431 - Cys-1074 - G432C - G1075C - K433C - K1076C - S434C - S1077C - T435C - T1078C - T436C - V1079C - V437C - V1080C - Q438C - Q1081C - L439C ϩ L1082C NDc a ϩ, cross-linked product not detected on SDS-PAGE.
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ABCB4 p.Gly432Cys 10806188:84:171
status: NEW
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