ABCB1 p.Gly455Ala
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PMID: 22028352
[PubMed]
Cayla G et al: "Clinical, angiographic, and genetic factors associated with early coronary stent thrombosis."
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Comment
61
The following variables were considered for inclusion in the comprehensive model: baseline demographic (age, sex, body mass index, smoking, and ancestry), clinical (hypertension, diabetes mellitus, previous myocar- dialinfarction,creatinineclearance Ͻ60 mL/min, left ventricular ejection fraction Ͻ40%, clopidogrel loading dose, and use of proton pump inhibitors [PPIs] and calcium channel blockers), and angiographic (American College of Cardiology/American Heart Association [ACC/AHA] type C lesion, number of vessels with disease, minimum stent diameter, acuteness of PCI, and post-PCI dissection) characteristics; predicted metabolic status (CYP2C19, CYP2C9, and CYP2B6); and genetic variants (CYP3A5*3, POR*28, PON1 Q192R and L55M, ABCB1 C3435T, P2Y12 H1/H2, ITGB3 T1565C, MTHFR C677T, PAI1 5G/ 4G, factor V G1691A, prothrombin G20210A, fibrinogen G455A, and VKORC1).
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ABCB1 p.Gly455Ala 22028352:61:865
status: NEW