PMID: 22028352

Cayla G, Hulot JS, O'Connor SA, Pathak A, Scott SA, Gruel Y, Silvain J, Vignalou JB, Huerre Y, de la Briolle A, Allanic F, Beygui F, Barthelemy O, Montalescot G, Collet JP
Clinical, angiographic, and genetic factors associated with early coronary stent thrombosis.
JAMA. 2011 Oct 26;306(16):1765-74., [PubMed]
Sentences
No. Mutations Sentence Comment
61 ABCB1 p.Gly455Ala
X
ABCB1 p.Gly455Ala 22028352:61:865
status: NEW
view ABCB1 p.Gly455Ala details
 The following variables were considered for inclusion in the comprehensive model: baseline demographic (age, sex, body mass index, smoking, and ancestry), clinical (hypertension, diabetes mellitus, previous myocar- dialinfarction,creatinineclearance Ͻ60 mL/min, left ventricular ejection fraction Ͻ40%, clopidogrel loading dose, and use of proton pump inhibitors [PPIs] and calcium channel blockers), and angiographic (American College of Cardiology/American Heart Association [ACC/AHA] type C lesion, number of vessels with disease, minimum stent diameter, acuteness of PCI, and post-PCI dissection) characteristics; predicted metabolic status (CYP2C19, CYP2C9, and CYP2B6); and genetic variants (CYP3A5*3, POR*28, PON1 Q192R and L55M, ABCB1 C3435T, P2Y12 H1/H2, ITGB3 T1565C, MTHFR C677T, PAI1 5G/ 4G, factor V G1691A, prothrombin G20210A, fibrinogen G455A, and VKORC1). Login to comment