ABCC11 p.Arg1096Lys
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PMID: 16863439
[PubMed]
Jedlitschky G et al: "Structure and function of the MRP2 (ABCC2) protein and its role in drug disposition."
No.
Sentence
Comment
72
Substitution of Arg at position 586 in rat Mrp2 with Leu and Ile and substitution of Arg at position 1096 with Lys, Leu and Met resulted in the acquisition of taurocholate transport activity, while retaining transport activity for GSH and glucuronate conjugates [42].
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ABCC11 p.Arg1096Lys 16863439:72:85
status: NEW