ABCA1 p.Asp2076Ala
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PMID: 15039072
[PubMed]
Roosbeek S et al: "Expression and activity of the nucleotide-binding domains of the human ABCA1 transporter."
No.
Sentence
Comment
85
To test if these residues are important for ATP binding and ATPase activity, we engineered and expressed the following mutations: A1061N, G1062N, D1064A, G1062Q + D1064A in NBD1, and T2073N, G2074N, D2076A, G2074Q+ D2076A in NBD2.
X
ABCA1 p.Asp2076Ala 15039072:85:199
status: NEWX
ABCA1 p.Asp2076Ala 15039072:85:215
status: NEW119 Size determination of WT and mutant ABCA1 His-NBD proteins by Dynamic Light Scattering: (s) His-NBD1 WT; (m) His-NBD1 (G1062Q + D1064A); (j) His-NBD1 (T1242 + T1243); (Ã) His-NBD2 WT; and (Ã) His-NBD2 (G2074Q + D2076A).
X
ABCA1 p.Asp2076Ala 15039072:119:221
status: NEW120 Size determination of WT and mutant ABCA1 His-NBD proteins by Dynamic Light Scattering: (s) His-NBD1 WT; (m) His-NBD1 (G1062Q + D1064A); (j) His-NBD1 (T1242 + T1243); () His-NBD2 WT; and () His-NBD2 (G2074Q + D2076A).
X
ABCA1 p.Asp2076Ala 15039072:120:211
status: NEW