ABCC9 p.Lys1075Met
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Comment
81
(53) As the excretion of phospholipids and cholesterol was not observed with MDR2- K435M or MDR2-K1075M, in which the Walker A lysine in either NBF was substituted by methionine, MDR2 mediates lipid efflux in an ATP-dependent manner, like other ABC transporters; however, no lipid secretion was observed from HEK293 cells expressing MDR1, even in the presence of bile salts.
X
ABCC9 p.Lys1075Met 17608770:81:97
status: NEW