ABCD1 p.Glu487Lys
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PMID: 16731973
[PubMed]
Rodriguez-Zavala JS et al: "Characterization of E. coli tetrameric aldehyde dehydrogenases with atypical properties compared to other aldehyde dehydrogenases."
No.
Sentence
Comment
160
The structure of the E487K enzyme revealed that the coenzyme-binding domain is destroyed, showing why NAD+ binds with such difficulty to the Asian variant (Larson et al. 2005).
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ABCD1 p.Glu487Lys 16731973:160:21
status: NEW
PMID: 16600530
[PubMed]
Lorenzo A et al: "Polymorphisms of alcohol-metabolizing enzymes and the risk for alcoholism and alcoholic liver disease in Caucasian Spanish women."
No.
Sentence
Comment
92
The ALDH2 SNP studied is a G to A transition in exon 12 which translates lysine instead of glutamic acid at the residue 487 (Glu487Lys).
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ABCD1 p.Glu487Lys 16600530:92:125
status: NEW