PMID: 16731973

Rodriguez-Zavala JS, Allali-Hassani A, Weiner H
Characterization of E. coli tetrameric aldehyde dehydrogenases with atypical properties compared to other aldehyde dehydrogenases.
Protein Sci. 2006 Jun;15(6):1387-96., [PubMed]
Sentences
No. Mutations Sentence Comment
160 ABCD1 p.Glu487Lys
X
ABCD1 p.Glu487Lys 16731973:160:21
status: NEW
view ABCD1 p.Glu487Lys details
 The structure of the E487K enzyme revealed that the coenzyme-binding domain is destroyed, showing why NAD+ binds with such difficulty to the Asian variant (Larson et al. 2005). Login to comment