ABCD1 p.Arg452Glu
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PMID: 17420574
[PubMed]
Endo A et al: "Identification of in vivo substrates of the chaperonin GroEL from Bacillus subtilis."
No.
Sentence
Comment
11
This mutant has four amino acid substitutions (R452E, E461A, S463A, and V464A, in E. coli GroEL) that prevent the formation of a double-ring structure and the release of GroES,7) and hence substrates can be observed to accumulate in the closed folding cage formed by the molecule.
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ABCD1 p.Arg452Glu 17420574:11:47
status: NEW