ABCC1 p.Gln834His
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PMID: 10099692
[PubMed]
Seino S et al: "ATP-sensitive potassium channels: a model of heteromultimeric potassium channel/receptor assemblies."
No.
Sentence
Comment
205
Mutations in the linker region between the Walker A motif and the Walker B motif of NBF-1 (G827D, G827R, and Q834H), the equivalent mutations in NBF-2 (G1479D, G1479R, G1485D, G1485R, Q1486H), or the mutation of Walker B motif of NBF-2 (D1506A) do not abolish channel inhibition by ATP (105).
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ABCC1 p.Gln834His 10099692:205:109
status: NEW211 Mutations in the linker region and the Walker B motif of NBF-2 (G1479D, G1479R, G1485D, G1485R, Q1486H, and D1506A) abolish channel activation by diazoxide, and mutations in the linker region of NBF-1 (G827D, G827R, and Q834H) alter the kinetics of diazoxide activation (106).
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ABCC1 p.Gln834His 10099692:211:220
status: NEW