ABCB1 p.Gln1280Ala
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PMID: 9371774
[PubMed]
Mechetner EB et al: "P-glycoprotein function involves conformational transitions detectable by differential immunoreactivity."
No.
Sentence
Comment
22
The mutant Pgps contain K433M and͞or K1076M substitutions in the Walker A motifs; in addition, the cloning procedure resulted in a Q1280A substitution of the C-terminal amino acid in all of the transfected MDR1 cDNA sequences.
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ABCB1 p.Gln1280Ala 9371774:22:137
status: NEW