ABCB1 p.Asn99Gln

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PMID: 16648557 [PubMed] Mutoh K et al: "A T3587G germ-line mutation of the MDR1 gene encodes a nonfunctional P-glycoprotein."
No. Sentence Comment
196 The SDS-PAGE profile of I1196S P-gp is also very similar to the glycosylation-deficient P-gp that has the three amino acid substitutions, N91Q, N94Q, and N99Q (39).
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ABCB1 p.Asn99Gln 16648557:196:154
status: NEW
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PMID: 11361134 [PubMed] Urbatsch IL et al: "Purification and characterization of N-glycosylation mutant mouse and human P-glycoproteins expressed in Pichia pastoris cells."
No. Sentence Comment
44 The N99Q mutation generates a new BciVI restriction site.
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ABCB1 p.Asn99Gln 11361134:44:4
status: NEW
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