ABCB1 p.Ala954Cys

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PMID: 16042402 [PubMed] Loo TW et al: "ATP hydrolysis promotes interactions between the extracellular ends of transmembrane segments 1 and 11 of human multidrug resistance P-glycoprotein."
No. Sentence Comment
158 Finally, we tested whether mutants M68C(TM1)/Y950C- (TM11), M68C(TM1)/Y953C(TM11), M68C(TM1)/A954C- (TM11), M69C(TM1)/A954C(TM11), and M69C(TM1)/ F957C(TM11) that showed ATP-dependent cross-linking were still active.
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ABCB1 p.Ala954Cys 16042402:158:93
status: NEW
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