ABCB1 p.Leu439Cys
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PMID: 11356825
[PubMed]
Urbatsch IL et al: "Cysteines 431 and 1074 are responsible for inhibitory disulfide cross-linking between the two nucleotide-binding sites in human P-glycoprotein."
No.
Sentence
Comment
301
In a previous report (42), inhibitory disulfide cross-linking was detected between the natural Cys-1074 residue in NBS2 of human Pgp and the engineered mutant residues Cys-427 (mutation G427C) and Cys-439 (mutation L439C) in NBS1.
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ABCB1 p.Leu439Cys 11356825:301:215
status: NEW299 In a previous report (42), inhibitory disulfide cross-linking was detected between the natural Cys-1074 residue in NBS2 of human Pgp and the engineered mutant residues Cys-427 (mutation G427C) and Cys-439 (mutation L439C) in NBS1.
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ABCB1 p.Leu439Cys 11356825:299:215
status: NEW