ABCB1 p.Phe335Leu
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PMID: 10400654
[PubMed]
Vo QD et al: "Identification of P-glycoprotein mutations causing a loss of steroid recognition and transport."
No.
Sentence
Comment
311
A F335L change caused decreased resistance to doxorubicin.
X
ABCB1 p.Phe335Leu 10400654:311:2
status: NEW
PMID: 8104183
[PubMed]
Loo TW et al: "Functional consequences of phenylalanine mutations in the predicted transmembrane domain of P-glycoprotein."
No.
Sentence
Comment
162
Phe335 to Leu or Tyr gave vinblastine/colchicine ratios of 1.1and 3.5, respectively.
X
ABCB1 p.Phe335Leu 8104183:162:0
status: NEW