ABCB1 p.Ser228Thr
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PMID: 10400654
[PubMed]
Vo QD et al: "Identification of P-glycoprotein mutations causing a loss of steroid recognition and transport."
No.
Sentence
Comment
301
Cell linea Drugb Mutation VINC DNR DEX PURO COLC ACT D MSPP-1 (1) NCc 2 222 2 ϩϩϩ NC W231L MSPP-7 (2) NC 22 222 22 ϩϩϩϩ NC W231L MSPP-55 (3) NC 2 222 22 ϩϩϩ NC W231L MSPP-6 (2) ϩ NC 222 22 22 NC H346N MSPP-17 (2) 2 22 222 22 22 NC A301T MSPP-4 (2) NC NC 222 2 2 NC A301V MSPP-35 (3) NC NC 222 NC 2 NC A301V MSPP-21 (2) 2 22 222 2 2 NC S228T a The numbers within the parentheses refer to the selection experiment in which the variant was isolated.
X
ABCB1 p.Ser228Thr 10400654:301:401
status: NEW
PMID: 12391288
[PubMed]
Gruol DJ et al: "Evidence for the locations of distinct steroid and Vinca alkaloid interaction domains within the murine mdr1b P-glycoprotein."
No.
Sentence
Comment
179
The most pronounced effect was caused by the S228T mutation expressed in the MSPP-21 cells.
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ABCB1 p.Ser228Thr 12391288:179:45
status: NEW