ABCC7 p.Phe833Leu
[switch to full view]Comments [show]
None has been submitted yet.
PMID: 21594798
[PubMed]
Kanelis V et al: "NMR spectroscopy to study the dynamics and interactions of CFTR."
No.
Sentence
Comment
127
As a disordered protein having a high fraction of charged residues, the R region was more easily amenable to solution NMR studies, once a better behaved construct containing the polymorphism F833L was identified (20).
X
ABCC7 p.Phe833Leu 21594798:127:191
status: NEW
PMID: 22278744
[PubMed]
Liang X et al: "Phosphorylation-dependent 14-3-3 protein interactions regulate CFTR biogenesis."
No.
Sentence
Comment
261
The human CFTR R region (654- 838; F833L) was expressed from a pPROEX HTb vector (Invitrogen) with an N-terminal hexahistidine tag and purified as described previously (Baker et al., 2007).
X
ABCC7 p.Phe833Leu 22278744:261:34
status: NEW262 (Note that the F833L polymorphism yields an R region that is significantly more soluble.)
X
ABCC7 p.Phe833Leu 22278744:262:15
status: NEW
PMID: 24191035
[PubMed]
Bozoky Z et al: "Regulatory R region of the CFTR chloride channel is a dynamic integrator of phospho-dependent intra- and intermolecular interactions."
No.
Sentence
Comment
237
The human CFTR R region (aa 654-838; F833L) was prepared as described in the work by Baker et al. (23), and the F833L polymorphism was used to optimize solubility.
X
ABCC7 p.Phe833Leu 24191035:237:37
status: NEWX
ABCC7 p.Phe833Leu 24191035:237:112
status: NEW