ABCC7 p.Gly970Glu
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PMID: 10453741
[PubMed]
Wagner JA et al: "Two novel mutations in a cystic fibrosis patient of Chinese origin."
No.
Sentence
Comment
102
Of interest, they found that the peak efflux for the construct G970E was about half that of WT, which is very similar to our result for the natural mutation G970D.
X
ABCC7 p.Gly970Glu 10453741:102:63
status: NEW
PMID: 8910333
[PubMed]
Seibert FS et al: "Cytoplasmic loop three of cystic fibrosis transmembrane conductance regulator contributes to regulation of chloride channel activity."
No.
Sentence
Comment
89
Introducing a negative charge (G970E) decreased iodide efflux while the introduction of a positive charge (G970K) again abolished CFTR function.
X
ABCC7 p.Gly970Glu 8910333:89:31
status: NEW