Mutations at homologous positions to ABCA10 p.Glu1168
Alignment: ABCA_full, Alignment of full length ABCA proteins, 2016-02-18 11:17:15Mutations exactly at the same position:
SNAP2 PROVEAN Effect_dbs |
||
---|---|---|
ABCA10 |
p.Glu1168Lys
|
N
N
?
|
Mutations +/- 5 a.a. around the position:
ABCA1 |
p.Asn1889Thr
|
N
N
?
|
The alignment around the queried position:
ABCA10 1144
I
M
N
K
D
P
V
F
R
-
I
S
P
R
S
R
E
-
-
-
-
-
-
-
-
-
-
-
-
-
-
T
H
P
N
P
E
E
P
E
E
D
E
D
V
Q
A
E
R
V
Q
A
A
N
A
L
T
A
P
N
L
E
E
E
P
V
I
T
A
S
C
L
H
K
E
Y
Y
E
T
1208
ABCA1 1861
V
V
F
F
L
I
T
V
I
Q
Y
R
F
F
I
R
P
R
-
-
-
-
-
-
-
-
-
-
-
-
P
V
N
A
K
L
S
P
L
D
E
D
E
D
V
R
E
R
Q
I
L
D
G
G
G
Q
-
-
-
-
-
N
D
I
L
E
I
K
E
L
T
K
I
Y
R
R
1923
ABCA2 2000
V
V
G
F
L
L
T
I
M
C
Q
Y
N
F
L
R
R
P
Q
-
-
-
-
-
-
-
-
-
-
-
-
R
M
P
V
S
T
K
P
V
E
D
-
D
V
D
V
A
S
E
R
Q
R
V
L
R
G
D
A
D
-
-
-
-
-
N
D
M
V
K
I
E
N
L
T
K
V
Y
K
S
2061
ABCA3 1315
C
A
Y
L
I
L
L
F
L
I
T
N
L
L
Q
R
L
G
I
L
C
A
L
R
R
R
R
T
L
T
E
L
Y
T
R
M
P
V
L
P
E
D
Q
D
V
D
E
R
T
R
I
L
A
P
S
P
D
S
L
L
-
-
H
T
P
L
I
K
E
L
S
K
V
Y
E
Q
1392
ABCA4 1887
V
V
Y
F
L
L
T
L
Q
H
F
L
S
Q
W
-
-
-
-
-
-
-
-
-
-
-
-
I
A
E
P
T
K
E
P
I
V
D
E
D
D
D
A
E
E
Q
R
I
I
T
G
G
N
K
-
-
-
-
-
T
D
I
L
R
H
L
T
K
I
Y
G
1949
ABCA5 1236
S
I
R
K
D
P
F
F
R
N
L
S
T
K
S
K
N
R
-
-
-
-
-
-
-
-
-
-
-
-
-
K
L
P
E
P
P
D
N
E
D
E
D
E
D
V
K
A
E
R
L
K
V
K
E
L
M
G
C
Q
C
C
E
E
K
P
S
I
M
V
S
N
L
H
K
E
Y
D
D
K
1302
ABCA6 1225
R
M
R
K
D
P
V
F
R
-
I
S
P
Q
S
R
D
-
-
-
-
-
-
-
-
-
-
-
-
-
-
A
K
P
N
P
E
E
P
I
D
E
D
E
D
I
Q
T
E
R
I
R
T
A
T
A
L
T
T
S
I
L
D
E
K
P
V
I
I
A
S
C
L
H
K
E
Y
A
G
Q
1289
ABCA7 1742
P
L
F
L
L
F
T
L
L
L
Q
H
R
S
Q
L
L
P
Q
-
-
-
-
-
-
-
-
-
-
-
-
P
R
V
R
S
L
P
L
L
G
E
E
D
E
D
V
A
R
E
R
V
V
Q
G
A
T
Q
-
-
-
-
-
G
D
V
L
V
L
R
N
L
T
K
V
Y
R
G
1804
ABCA8 1188
S
M
R
K
D
P
F
F
R
-
I
S
P
R
S
S
D
-
-
-
-
-
-
-
-
-
-
-
-
-
-
V
C
Q
N
P
E
E
P
E
G
E
D
E
D
V
Q
M
E
R
V
R
T
A
N
A
L
N
S
T
N
F
D
E
K
P
V
I
I
A
S
C
L
R
K
E
Y
A
G
K
1252
ABCA9 1231
L
M
R
K
D
P
V
F
R
-
I
S
P
R
S
N
A
-
-
-
-
-
-
-
-
-
-
-
-
-
-
I
F
P
N
P
E
E
P
E
G
E
E
E
D
I
Q
M
E
R
M
R
T
V
N
A
M
A
V
R
D
F
D
E
T
P
V
I
I
A
S
C
L
R
K
E
Y
A
G
K
1295
ABCA12 2198
T
M
F
F
S
L
R
L
L
I
N
E
S
L
I
K
K
L
R
-
-
-
-
-
-
-
L
F
F
R
K
F
N
S
S
H
V
R
E
T
I
D
E
D
E
D
V
R
A
E
R
L
R
V
E
S
G
A
A
E
-
-
-
-
-
F
D
L
V
Q
L
Y
C
L
T
K
T
Y
Q
L
2265
ABCA13 4666
T
V
L
L
L
L
R
V
L
L
H
W
D
L
L
R
-
-
-
-
-
-
-
-
-
-
-
W
P
R
G
H
S
T
L
Q
G
T
V
K
S
S
K
D
T
D
V
E
K
E
E
K
R
V
F
E
G
R
T
N
-
-
-
-
-
G
D
I
L
V
L
Y
N
L
S
K
H
Y
R
4729