Mutations at homologous positions to ABCA4 p.Leu725

Alignment: ABCA_full, Alignment of full length ABCA proteins, 2016-02-18 11:17:15

Mutations exactly at the same position:

Mutations +/- 5 a.a. around the position:

The alignment around the queried position:

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 3758
ABCA4 691
V
S
N
A
V
I
W
C
T
W
F
L
D
S
F
S
I
M
S
M
S
I
F
L
L
T
I
F
I
M
H
G
-
-
-
-
-
R
I
L
H
Y
S
D
P
F
I
L
F
L
F
L
L
A
F
S
T
A
T
I
M
L
C
F
L
L
S
T
F
F
S
K
A
S
L
A
A
A
C
S
 765
ABCA1 676
L
D
N
S
I
L
W
F
S
W
F
I
S
S
L
I
P
L
L
V
S
A
G
L
L
V
V
I
L
K
L
G
-
-
-
-
-
N
L
L
P
Y
S
D
P
S
V
V
F
V
F
L
S
V
F
A
V
V
T
I
L
Q
C
F
L
I
S
T
L
F
S
R
A
N
L
A
A
A
C
G
 750
ABCA2 743
L
N
N
A
V
H
W
V
A
W
F
I
T
G
F
V
Q
L
S
I
S
V
T
A
L
T
A
I
L
K
Y
G
-
-
-
-
-
Q
V
L
M
H
S
H
V
V
I
I
W
L
F
L
A
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Y
A
V
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T
I
M
F
C
F
L
V
S
V
L
Y
S
K
A
K
L
A
S
A
C
G
 817
ABCA3 299
L
S
S
W
L
H
W
S
A
W
F
L
L
F
F
L
F
L
L
I
A
A
S
F
M
T
L
L
F
C
V
K
V
K
P
N
V
A
V
L
S
R
S
D
P
S
L
V
L
A
F
L
L
C
F
A
I
S
T
I
S
F
S
F
M
V
S
T
F
F
S
K
A
N
M
A
A
A
F
G
 378
ABCA5 258
H
D
T
A
F
W
L
S
W
V
L
L
Y
T
S
L
I
F
L
M
S
L
L
M
A
V
I
A
T
A
S
-
-
-
-
-
L
L
F
P
Q
S
S
S
I
V
I
F
L
L
F
F
L
Y
G
L
S
S
V
F
F
A
L
M
L
T
P
L
F
K
K
S
-
-
-
-
K
H
V
G
 328
ABCA6 259
Q
D
S
A
F
W
L
S
W
G
L
I
Y
A
G
F
I
F
I
I
S
I
F
V
T
I
I
I
T
F
T
-
-
-
-
-
Q
I
I
V
M
T
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F
M
V
I
F
I
L
F
F
L
Y
G
L
S
L
V
A
L
V
F
L
M
S
V
L
L
K
K
A
-
-
-
-
V
L
T
N
 329
ABCA7 586
L
S
R
A
V
L
W
L
G
W
F
L
S
C
L
G
P
F
L
L
S
A
A
L
L
V
L
V
L
K
L
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-
-
-
-
-
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I
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V
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F
L
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L
A
A
F
A
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A
T
V
T
Q
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F
L
L
S
A
F
F
S
R
A
N
L
A
A
A
C
G
 660
ABCA8 261
R
D
S
A
F
W
L
S
W
G
L
L
Y
A
G
F
I
F
I
M
A
L
F
L
A
L
V
I
R
S
T
-
-
-
-
-
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F
I
I
L
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L
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L
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A
L
A
F
L
M
S
I
L
V
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K
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-
-
-
-
F
L
T
G
 331
ABCA9 262
R
E
S
A
F
W
L
S
W
G
L
M
Y
A
G
F
I
L
I
M
A
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L
M
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L
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V
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S
A
-
-
-
-
-
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F
L
M
S
V
L
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-
-
-
-
F
L
T
G
 332
ABCA10 172
R
E
S
A
F
W
L
S
W
G
L
T
Y
I
C
F
I
F
I
M
S
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T
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-
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-
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A
L
A
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L
M
S
V
L
I
R
K
P
-
-
-
-
M
L
A
G
 242
ABCA12 1105
V
N
S
C
S
H
F
F
A
W
L
I
E
S
V
G
F
L
L
V
T
I
V
I
L
I
I
I
L
K
F
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-
-
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Y
L
I
S
V
F
F
N
N
T
N
I
A
A
L
I
G
 1179
ABCA13 3608
V
H
P
V
I
H
F
L
A
W
F
L
E
N
M
A
V
L
T
I
S
S
A
T
L
A
I
V
L
K
T
S
-
-
-
-
-
G
I
F
A
H
S
N
T
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V
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L
F
L
L
D
F
G
M
S
V
V
M
L
S
Y
L
L
S
A
F
F
S
Q
A
N
T
A
A
L
C
T
 3682