Mutations at homologous positions to ABCA4 p.Thr1253

Alignment: ABCA_full, Alignment of full length ABCA proteins, 2016-02-18 11:17:15

Mutations exactly at the same position:

Mutations +/- 5 a.a. around the position:

The alignment around the queried position:

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 4307
ABCA4 1215
H
V
P
E
A
K
L
V
E
C
I
G
Q
E
L
I
F
L
L
P
N
K
N
F
K
H
R
-
A
Y
A
S
L
F
R
E
L
E
E
T
L
A
D
L
G
L
S
S
F
G
I
S
D
T
P
L
E
E
I
F
L
K
V
T
E
D
S
D
S
G
P
L
F
A
G
G
A
Q
Q
K
 1293
ABCA1 1190
H
V
S
E
A
R
L
V
E
D
I
G
H
E
L
T
Y
V
L
P
Y
E
A
A
K
E
G
-
A
F
V
E
L
F
H
E
I
D
D
R
L
S
D
L
G
I
S
S
Y
G
I
S
E
T
T
L
E
E
I
F
L
K
V
A
E
E
S
G
V
D
A
E
T
S
D
G
T
L
P
A
 1268
ABCA2 1260
H
V
A
S
C
L
L
V
S
D
T
S
T
E
L
S
Y
I
L
P
S
E
A
A
K
K
G
-
A
F
E
R
L
F
Q
H
L
E
R
S
L
D
A
L
H
L
S
S
F
G
L
M
D
T
T
L
E
E
V
F
L
K
V
S
E
E
D
Q
S
L
E
N
S
E
A
D
V
K
E
S
 1338
ABCA3 780
H
V
P
N
A
T
L
E
S
S
A
G
A
E
L
S
F
I
L
P
R
E
S
T
H
R
-
-
-
F
E
G
L
F
A
K
L
E
K
K
Q
K
E
L
G
I
A
S
F
G
A
S
I
T
T
M
E
E
V
F
L
R
V
G
K
L
V
D
S
S
M
D
I
Q
A
I
Q
L
P
A
 856
ABCA5 731
I
P
G
A
T
L
L
Q
Q
N
D
Q
Q
L
V
Y
S
L
P
F
K
D
M
D
K
-
-
-
F
S
G
L
F
S
A
L
D
S
-
H
S
N
L
G
V
I
S
Y
G
V
S
M
T
T
L
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D
V
F
L
K
L
E
V
E
A
E
I
D
Q
A
D
Y
S
V
F
T
Q
Q
P
 806
ABCA6 731
I
P
D
A
K
L
K
T
E
N
K
E
K
L
V
Y
T
L
P
L
E
R
T
N
T
-
-
-
F
P
D
L
F
S
D
L
D
K
-
C
S
D
Q
G
V
T
G
Y
D
I
S
M
S
T
L
N
E
V
F
M
K
L
E
G
Q
S
T
I
E
Q
D
-
-
-
-
-
-
F
E
Q
 800
ABCA7 1085
W
V
P
G
A
R
L
V
E
E
L
P
H
E
L
V
L
V
L
P
Y
T
G
A
H
D
G
-
S
F
A
T
L
F
R
E
L
D
T
R
L
A
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L
R
L
T
G
Y
G
I
S
D
T
S
L
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I
F
L
K
V
V
E
E
C
A
A
D
T
D
M
E
D
G
S
C
G
Q
 1163
ABCA8 693
I
P
D
A
K
L
S
A
K
S
E
G
K
L
I
Y
T
L
P
L
E
R
T
N
K
-
-
-
F
P
E
L
Y
K
D
L
D
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-
Y
P
D
L
G
I
E
N
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G
V
S
M
T
T
L
N
E
V
F
L
K
L
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G
K
S
T
I
N
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S
D
I
A
I
L
G
E
V
Q
 768
ABCA9 734
I
S
D
A
K
L
T
A
Q
S
E
E
K
L
V
Y
I
L
P
L
E
R
T
N
K
-
-
-
F
P
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L
Y
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D
L
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L
K
L
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D
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G
I
W
G
Q
L
Q
 809
ABCA10 644
I
P
D
A
K
L
T
T
E
S
E
E
K
L
V
Y
S
L
P
L
E
K
T
N
K
-
-
-
F
P
D
L
Y
S
D
L
D
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C
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N
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A
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V
T
S
L
N
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F
L
N
L
E
G
K
S
A
I
D
E
P
D
F
D
I
G
K
Q
E
K
 719
ABCA12 1602
H
L
P
E
A
Y
L
K
E
D
I
G
G
E
L
V
Y
V
L
P
P
F
S
T
K
V
S
G
A
Y
L
S
L
L
R
A
L
D
N
G
M
G
D
L
N
I
G
C
Y
G
I
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D
T
T
V
E
E
V
F
L
N
L
T
K
E
S
Q
K
N
S
A
M
S
L
E
H
L
T
Q
 1681
ABCA13 4098
Y
I
P
Q
A
F
L
K
D
S
S
G
S
E
L
T
Y
T
I
P
K
D
T
D
K
A
C
-
-
L
K
G
L
F
Q
A
L
D
E
N
L
H
Q
L
H
L
T
G
Y
G
I
S
D
T
T
L
E
E
V
F
L
M
L
L
Q
D
S
N
K
K
S
H
I
A
L
G
-
-
T
E
 4173