Mutations at homologous positions to ABCA1 p.Lys1974

Alignment: ABCA_full, Alignment of full length ABCA proteins, 2016-02-18 11:17:15

Mutations exactly at the same position:

Mutations +/- 5 a.a. around the position:

The alignment around the queried position:

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 5170
ABCA1 1939
G
E
C
F
G
L
L
G
V
N
G
A
G
K
S
S
T
F
K
M
L
T
G
D
T
T
V
T
R
G
D
A
F
L
N
-
-
-
-
K
N
S
I
L
S
N
I
H
E
V
H
Q
N
M
G
Y
C
P
Q
F
D
A
I
T
E
L
L
T
G
R
E
H
V
E
F
F
A
L
L
R
 2014
ABCA2 2080
G
E
C
F
G
L
L
G
V
N
G
A
G
K
T
S
T
F
K
M
L
T
G
D
E
S
T
T
G
G
E
A
F
V
N
-
-
-
-
G
H
S
V
L
K
E
L
L
Q
V
Q
Q
S
L
G
Y
C
P
Q
C
D
A
L
F
D
E
L
T
A
R
E
H
L
Q
L
Y
T
R
L
R
 2155
ABCA3 1409
G
E
C
F
G
L
L
G
F
N
G
A
G
K
T
T
T
F
K
M
L
T
G
E
E
S
L
T
S
G
D
A
F
V
G
-
-
-
-
G
H
R
I
S
S
D
V
G
K
V
R
Q
R
I
G
Y
C
P
Q
F
D
A
L
L
D
H
M
T
G
R
E
M
L
V
M
Y
A
R
L
R
 1484
ABCA4 1965
G
E
C
F
G
L
L
G
V
N
G
A
G
K
T
T
T
F
K
M
L
T
G
D
T
T
V
T
S
G
D
A
T
V
A
-
-
-
-
G
K
S
I
L
T
N
I
S
E
V
H
Q
N
M
G
Y
C
P
Q
F
D
A
I
D
E
L
L
T
G
R
E
H
L
Y
L
Y
A
R
L
R
 2040
ABCA5 1327
E
I
L
G
L
L
G
P
N
G
A
G
K
S
T
I
I
N
I
L
V
G
D
I
E
P
T
S
G
Q
V
F
L
G
D
Y
-
-
S
S
E
T
S
E
-
D
D
D
S
L
K
C
M
G
Y
C
P
Q
I
N
P
L
W
P
D
T
T
L
Q
E
H
F
E
I
Y
G
A
V
K
G
 1403
ABCA6 1314
E
I
L
G
L
L
G
P
N
G
A
G
K
S
S
S
I
R
M
I
S
G
I
T
K
P
T
A
G
E
V
E
L
K
G
-
-
-
-
-
-
-
-
-
-
C
S
S
V
L
G
H
L
G
Y
C
P
Q
E
N
V
L
W
P
M
L
T
L
R
E
H
L
E
V
Y
A
A
V
K
G
 1383
ABCA7 1820
G
E
C
F
G
L
L
G
V
N
G
A
G
K
T
S
T
F
R
M
V
T
G
D
T
L
A
S
R
G
E
A
V
L
A
-
-
-
-
G
H
S
V
A
R
E
P
S
A
A
H
L
S
M
G
Y
C
P
Q
S
D
A
I
F
E
L
L
T
G
R
E
H
L
E
L
L
A
R
L
R
 1895
ABCA8 1277
E
V
L
G
L
L
G
H
N
G
A
G
K
S
T
S
I
K
V
I
T
G
D
T
K
P
T
A
G
Q
V
L
L
K
G
S
-
-
G
-
-
-
-
-
-
G
G
D
A
L
E
F
L
G
Y
C
P
Q
E
N
A
L
W
P
N
L
T
V
R
Q
H
L
E
V
Y
A
A
V
K
G
 1348
ABCA9 1320
E
V
I
G
L
L
G
H
N
G
A
G
K
S
T
T
I
K
M
I
T
G
D
T
K
P
T
A
G
Q
V
I
L
K
G
S
-
-
G
-
-
-
-
-
-
G
G
E
P
L
G
F
L
G
Y
C
P
Q
E
N
A
L
W
P
N
L
T
V
R
Q
H
L
E
V
Y
A
A
V
K
G
 1391
ABCA10 1233
E
V
L
G
L
L
G
H
N
G
A
G
K
S
T
S
I
K
M
I
T
G
C
T
K
P
T
A
G
V
V
V
L
Q
G
S
-
-
R
A
S
V
R
Q
Q
H
D
N
S
L
K
F
L
G
Y
C
P
Q
E
N
S
L
W
P
K
L
T
M
K
E
H
L
E
L
Y
A
A
V
K
G
 1310
ABCA12 2283
G
E
C
F
G
L
L
G
V
N
G
A
G
K
T
T
I
F
K
M
L
T
G
D
I
I
P
S
S
G
N
I
L
I
R
N
K
T
G
-
-
-
S
L
G
H
V
D
S
H
S
S
L
V
G
Y
C
P
Q
E
D
A
L
D
D
L
V
T
V
E
E
H
L
Y
F
Y
A
R
V
H
 2359
ABCA13 4747
G
E
C
F
G
L
L
G
V
N
G
A
G
K
S
T
T
F
K
M
L
N
G
E
V
S
L
T
S
G
H
A
I
I
R
T
P
M
G
D
A
V
D
L
S
S
A
G
T
A
G
V
L
I
G
Y
C
P
Q
Q
D
A
L
D
E
L
L
T
G
W
E
H
L
Y
Y
Y
C
S
L
R
 4826