Mutations at homologous positions to ABCA1 p.Asn1889
Alignment: ABCA_full, Alignment of full length ABCA proteins, 2016-02-18 11:17:15Mutations exactly at the same position:
SNAP2 PROVEAN Effect_dbs |
||
---|---|---|
ABCA1 |
p.Asn1889Thr
|
N
N
?
|
Mutations +/- 5 a.a. around the position:
ABCA10 |
p.Glu1168Lys
|
N
N
?
|
The alignment around the queried position:
ABCA1 1862
V
F
F
L
I
T
V
I
Q
Y
R
F
F
I
R
P
R
-
-
-
-
-
-
-
-
-
-
-
-
P
V
N
A
K
L
S
P
L
D
E
D
E
D
V
R
E
R
Q
I
L
D
G
G
G
Q
-
-
-
-
-
N
D
I
L
E
I
K
E
L
T
K
I
Y
R
R
K
1924
ABCA2 2001
V
G
F
L
L
T
I
M
C
Q
Y
N
F
L
R
R
P
Q
-
-
-
-
-
-
-
-
-
-
-
-
R
M
P
V
S
T
K
P
V
E
D
-
D
V
D
V
A
S
E
R
Q
R
V
L
R
G
D
A
D
-
-
-
-
-
N
D
M
V
K
I
E
N
L
T
K
V
Y
K
S
R
2062
ABCA3 1316
A
Y
L
I
L
L
F
L
I
T
N
L
L
Q
R
L
G
I
L
C
A
L
R
R
R
R
T
L
T
E
L
Y
T
R
M
P
V
L
P
E
D
Q
D
V
D
E
R
T
R
I
L
A
P
S
P
D
S
L
L
-
-
H
T
P
L
I
K
E
L
S
K
V
Y
E
Q
R
1393
ABCA4 1888
V
Y
F
L
L
T
L
Q
H
F
L
S
Q
W
-
-
-
-
-
-
-
-
-
-
-
-
I
A
E
P
T
K
E
P
I
V
D
E
D
D
D
A
E
E
Q
R
I
I
T
G
G
N
K
-
-
-
-
-
T
D
I
L
R
H
L
T
K
I
Y
G
T
1950
ABCA5 1237
I
R
K
D
P
F
F
R
N
L
S
T
K
S
K
N
R
-
-
-
-
-
-
-
-
-
-
-
-
-
K
L
P
E
P
P
D
N
E
D
E
D
E
D
V
K
A
E
R
L
K
V
K
E
L
M
G
C
Q
C
C
E
E
K
P
S
I
M
V
S
N
L
H
K
E
Y
D
D
K
K
1303
ABCA6 1226
M
R
K
D
P
V
F
R
-
I
S
P
Q
S
R
D
-
-
-
-
-
-
-
-
-
-
-
-
-
-
A
K
P
N
P
E
E
P
I
D
E
D
E
D
I
Q
T
E
R
I
R
T
A
T
A
L
T
T
S
I
L
D
E
K
P
V
I
I
A
S
C
L
H
K
E
Y
A
G
Q
K
1290
ABCA7 1743
L
F
L
L
F
T
L
L
L
Q
H
R
S
Q
L
L
P
Q
-
-
-
-
-
-
-
-
-
-
-
-
P
R
V
R
S
L
P
L
L
G
E
E
D
E
D
V
A
R
E
R
V
V
Q
G
A
T
Q
-
-
-
-
-
G
D
V
L
V
L
R
N
L
T
K
V
Y
R
G
Q
1805
ABCA8 1189
M
R
K
D
P
F
F
R
-
I
S
P
R
S
S
D
-
-
-
-
-
-
-
-
-
-
-
-
-
-
V
C
Q
N
P
E
E
P
E
G
E
D
E
D
V
Q
M
E
R
V
R
T
A
N
A
L
N
S
T
N
F
D
E
K
P
V
I
I
A
S
C
L
R
K
E
Y
A
G
K
R
1253
ABCA9 1232
M
R
K
D
P
V
F
R
-
I
S
P
R
S
N
A
-
-
-
-
-
-
-
-
-
-
-
-
-
-
I
F
P
N
P
E
E
P
E
G
E
E
E
D
I
Q
M
E
R
M
R
T
V
N
A
M
A
V
R
D
F
D
E
T
P
V
I
I
A
S
C
L
R
K
E
Y
A
G
K
K
1296
ABCA10 1145
M
N
K
D
P
V
F
R
-
I
S
P
R
S
R
E
-
-
-
-
-
-
-
-
-
-
-
-
-
-
T
H
P
N
P
E
E
P
E
E
D
E
D
V
Q
A
E
R
V
Q
A
A
N
A
L
T
A
P
N
L
E
E
E
P
V
I
T
A
S
C
L
H
K
E
Y
Y
E
T
K
1209
ABCA12 2199
M
F
F
S
L
R
L
L
I
N
E
S
L
I
K
K
L
R
-
-
-
-
-
-
-
L
F
F
R
K
F
N
S
S
H
V
R
E
T
I
D
E
D
E
D
V
R
A
E
R
L
R
V
E
S
G
A
A
E
-
-
-
-
-
F
D
L
V
Q
L
Y
C
L
T
K
T
Y
Q
L
I
2266
ABCA13 4667
V
L
L
L
L
R
V
L
L
H
W
D
L
L
R
-
-
-
-
-
-
-
-
-
-
-
W
P
R
G
H
S
T
L
Q
G
T
V
K
S
S
K
D
T
D
V
E
K
E
E
K
R
V
F
E
G
R
T
N
-
-
-
-
-
G
D
I
L
V
L
Y
N
L
S
K
H
Y
R
F
4730