Mutations at homologous positions to ABCA4 p.Leu11
Alignment: ABCA_full, Alignment of full length ABCA proteins, 2016-02-18 11:17:15Mutations exactly at the same position:
|
SNAP2 PROVEAN Effect_dbs |
||
|---|---|---|
| ABCA4 |
p.Leu11Pro
|
D
D
|
Mutations +/- 5 a.a. around the position:
| ABCA4 |
p.Trp15*
|
-
-
|
| ABCA3 |
p.Trp12*
|
-
-
?
|
The alignment around the queried position:
ABCA4 1
-
G
F
V
R
Q
I
Q
L
L
W
K
N
T
L
K
R
K
I
F
V
E
L
V
P
L
S
L
F
L
V
L
I
L
R
N
A
N
P
L
Y
S
H
51
ABCA1 1
-
M
A
C
W
P
Q
L
R
L
L
L
W
K
N
L
T
F
R
R
R
Q
T
Q
L
L
L
E
V
A
W
P
L
F
I
F
L
I
L
I
S
V
R
S
Y
P
P
Y
E
Q
51
ABCA2 1
-
M
G
F
L
H
Q
L
Q
L
L
L
W
K
N
V
T
L
K
R
R
S
P
W
V
L
A
F
E
I
F
I
P
L
V
L
F
F
I
L
L
G
L
R
Q
K
K
P
T
I
S
V
51
ABCA3 1
-
M
A
V
L
R
Q
L
A
L
L
L
K
N
Y
T
L
Q
K
K
V
L
V
T
V
L
E
L
F
L
P
L
L
F
S
G
I
I
W
L
L
K
-
-
-
-
-
-
46
ABCA5 1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
ABCA6 1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
ABCA7 1
-
M
A
F
W
T
Q
L
M
L
L
L
W
K
N
F
M
Y
R
R
R
Q
P
V
Q
L
L
V
E
L
L
W
P
L
F
L
F
F
I
L
V
A
V
R
H
S
H
P
P
L
E
H
51
ABCA8 1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
ABCA9 1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
ABCA10 1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
ABCA12 1
M
A
S
L
F
H
Q
L
Q
I
L
V
W
K
N
W
L
G
V
K
R
Q
P
L
W
T
L
V
L
I
L
W
P
V
I
I
F
I
I
L
A
I
T
R
T
K
F
P
P
T
A
K
52
ABCA13 1
M
G
H
A
G
C
Q
F
K
A
L
L
W
K
N
W
L
C
R
L
R
N
P
V
L
F
L
A
E
F
F
W
P
C
I
L
F
V
I
L
T
V
L
R
F
Q
E
P
P
R
Y
R
52