PMID: 9851885

Morrow SL, Larson JE, Nelson S, Sekhon HS, Ren T, Cohen JC
Modification of development by the CFTR gene in utero.
Mol Genet Metab. 1998 Nov;65(3):203-12., [PubMed]
Sentences
No. Mutations Sentence Comment
22 ABCC7 p.Ser489*
X
ABCC7 p.Ser489* 9851885:22:106
status: NEW
view ABCC7 p.Ser489* details
 A recombinant adenovirus containing human cftr (Av1CF2 [10]) was used for in utero gene transfer into the S489X cftr knockout mouse (C57Bl/ 1 To whom correspondence should be addressed at Ochsner Medical Foundation, Department of Molecular Genetics, 1516 Jefferson Highway, New Orleans, LA 70121. Login to comment 28 ABCC7 p.Ser489*
X
ABCC7 p.Ser489* 9851885:28:0
status: NEW
view ABCC7 p.Ser489* details
 S489X cftr (2/2) mice develop a lethal intestinal obstruction resulting in less than 5% survival to adulthood (.40 days) (11). Login to comment 29 ABCC7 p.Ser489*
X
ABCC7 p.Ser489* 9851885:29:0
status: NEW
view ABCC7 p.Ser489* details
 S489X cftr (-/-) mice develop a lethal intestinal obstruction resulting in less than 5% survival to adulthood (Ͼ40 days) (11). Login to comment