PMID: 9748559

Arias HR
Binding sites for exogenous and endogenous non-competitive inhibitors of the nicotinic acetylcholine receptor.
Biochim Biophys Acta. 1998 Aug 21;1376(2):173-220., [PubMed]
Sentences
No. Mutations Sentence Comment
1363 ABCC8 p.Cys418Trp
X
ABCC8 p.Cys418Trp 9748559:1363:132
status: NEW
view ABCC8 p.Cys418Trp details
 The importance of the serine ring in regards to NCI binding is also based on the fact that mutations distant from this locus (e.g., Cys418 to Trp at KM4) have shown no alteration in PCP and tetracaine noncompetitive inhibition properties [144]. Login to comment