PMID: 9398248

Dayan G, Jault JM, Baubichon-Cortay H, Baggetto LG, Renoir JM, Baulieu EE, Gros P, Di Pietro A
Binding of steroid modulators to recombinant cytosolic domain from mouse P-glycoprotein in close proximity to the ATP site.
Biochemistry. 1997 Dec 9;36(49):15208-15., 1997-12-09 [PubMed]
Sentences
No. Mutations Sentence Comment
132 ABCB1 p.Thr581Glu
X
ABCB1 p.Thr581Glu 9398248:132:84
status: NEW
view ABCB1 p.Thr581Glu details
 In the latter case, it was clearly shown that increasing the C-side extension, from threonine-581 to glutamate-613 or serine-643, gradually lowered the protein solubility during overexpression. Login to comment