PMID: 9063876

Ostedgaard LS, Rich DP, DeBerg LG, Welsh MJ
Association of domains within the cystic fibrosis transmembrane conductance regulator.
Biochemistry. 1997 Feb 11;36(6):1287-94., [PubMed]
Sentences
No. Mutations Sentence Comment
207 ABCC7 p.Gly91Arg
X
ABCC7 p.Gly91Arg 9063876:207:74
status: NEW
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 We made an N-terminal construct that contained the CF-associated mutation G91R (Guillermit et al., 1993) in M1 (1-835G91R) and expressed it alone or with the C-terminal half, 837-1480. Login to comment 209 ABCC7 p.Gly85Glu
X
ABCC7 p.Gly85Glu 9063876:209:56
status: NEW
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ABCC7 p.Glu92Lys
X
ABCC7 p.Glu92Lys 9063876:209:47
status: NEW
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 Two other naturally occurring mutations in M1, E92K and G85E (Nunes et al., 1993; Zielenski et al., 1991), also failed to disrupt associations between halves. Login to comment