ABCMdb

PMID: 8913585

Zhao J, Zerhusen B, Xie J, Drumm ML, Davis PB, Ma J
Rectification of cystic fibrosis transmembrane conductance regulator chloride channel mediated by extracellular divalent cations.
Biophys J. 1996 Nov;71(5):2458-66., [PubMed]

Sentences

No. Mutations Sentence Comment

190 ABCC7 p.Arg347Asp ABCC7 p.Lys335Glu The studies of Tabcharani et al. (1993) showed that TM6 is also involved in the conduction process of the CFTR channel, as point mutations of K335E and R347D altered the multi-ion pore behavior of the CFTR channel. Login to comment 191 ABCC7 p.Arg347Asp ABCC7 p.Lys335Glu The studies of Tabcharani et al. (1993) showed that TM6 is also involved in the conduction process of the CFTR channel, as point mutations of K335E and R347D altered the multi-ion pore behavior of the CFTR channel. Login to comment